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Cardiovascular disease, cancer experts in Chongqing key signaling molecule – Cancer – Pharmaceutical

Cardiovascular disease, cancer experts in Chongqing key signaling molecule – Cancer – Pharmaceutical

Article by jekky

January 23 was included in the national quot 973 Plan quot pre project quot Cancer And new methods of prevention and treatment of cardiovascular disease quot Daping Hospital Third Military Medical University Institute of Field Surgery passed the acceptance of the Expert Group Finished The project leukemia Hepatic carcinoma Cancer and other common diseases with multiple mechanisms of cancer has made significant progress in hypertension coronary heart disease cardiac arrhythmias and other cardiovascular disease pathogenesis there are new discoveries Cancer and cardiovascular disease is recognized worldwide human health killer effective prevention and treatment are medically urgent need to solve two major problems of prevention treatment new method for reducing cancer cardiovascular disease prevalence improve human health and quality of life is of great significance By the Daping Hospital Third Military Medical University Institute of Field Surgery Professor of cardiovascular medicine general coordinator of rain as a project featuring this item from the March 2008 establishment through the joint effort of 11 discussion group for two years at the molecular protein levels found in cancer cardiovascular disease in the key signaling molecule to enable mankind through the intervention of these key signaling molecules and target proteins and effective prevention and treatment of major diseases such possible treatment for developing drugs vaccines provide a new way of thinking Mechanism of cancer prevention and control through cross border gene silencing mechanism in the digestive system tumors and treatment of colon cancer stem cells in the malignant behavior of associated genes and their functional identification of leukemia from normal hematopoietic injury Mechanism of research in the field of study full use of stem cell technology molecular biology tools immunology technology bioinformatics and other means of tumor abnormal signal pathway the key function of target proteins and abnormal regulation of molecules stem cell injury and the screening malignant behavior of cancer cells genetically complex diseases such as the contents of the target gene function identification for tumor detection prevention and the development potential of targeted therapy to provide a theoretical basis for the cancer stem cell research a key molecular target in tumors and cancer Transfer the field of bioinformatics was a large number of research results By G protein kinase 4 in the pathogenesis of essential hypertension and the mechanisms of inflammation caused by atherosclerosis foam cell formation and potency of statins durable potential new mechanism for promoting apoptosis related kinase gene in coronary heart disease the role of the pathogenesis of basic research malignant ventricular arrhythmia mechanism and biological research treatment of hypertension coronary heart disease malignant arrhythmia mechanism was analyzed to confirm the G protein kinase 4 variant of renal dopamine receptors exist as network dysfunction reason to interfere with G protein kinase 4 as a new drug target in hypertension research and development to correct the dysfunction of multiple systems function to achieve the step down purposes revealed promote apoptosis related kinase signaling pathway and inflammatory cytokines induced abnormal cell Cholesterol Synthesis in the pathogenesis of coronary heart disease relationships and molecular mechanisms of ischemic Heart disease With heart failure produce malignant ventricular arrhythmia mechanism for coronary heart disease and malignant ventricular arrhythmias and the prevention and treatment interventions targeted to provide a new strategy in coronary heart disease hypertension arrhythmia etc also in the pathogenesis of cardiovascular research found abnormal receptor target genes and abnormal network of clinical intervention for the future occurrence of cancer and cardiovascular disease provides a theoretical basis In the subject of funding a number of innovative academic team beginning to take shape there are 13 professors have received National Outstanding Youth Fund the Changjiang Scholars the National 100 million project to train other honors received a number of science and technology award 7 patent applications training more than 40 doctoral students 50 graduate students of whom 100 received the National Excellent Doctoral Dissertation 1

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